Research

Asymmetric catalysis

We aim to develop new strategies for asymmetric synthesis, and use mechanistic insight to guide the process of discovering and improving new catalytic reactions.

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ACS Catalysis 2019, 9, 7179−7187.

 

Total Synthesis

Completed targets include prostaglandin analogue Tafluprost, the natural product isoanabasine, the antipsychotic preclamol and the recently approved anticancer agent Niraparib as well as fragrances phenoxanol and hyroxycitronellal.

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Org. Lett. 2020, 222991-2994.

Origins of Life

We are working toward understanding how the most basic functions of life can be observed in purely synthetic systems by studying self-replicators that operate far-from-equilibrium.

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Nature Communications 2019, 10, 1011.